APO-Furosemide (Furosemide USP) 40MG by Apotex Inc.
It inhibits the reabsorption of sodium ions in the ascending knee of the Henle loop, proximal and distal tubules. Increases the excretion of bicarbonates, phosphates, calcium, magnesium.
- Edema with circulatory failure, liver and kidney disease, difficulty in venous outflow, after burns and phlebothrombosis;
- Ascites (against a background of malignant neoplasm, hepatic and cardiac origin);
- Peripheral edema;
- Pulmonary edema, incl. post-traumatic cerebral edema, arterial hypertension;
- Toxicosis of pregnancy, generic eclampsia, premenstrual tension syndrome, preterm uremia, hyperkalemia, carrying out forced diuresis (poisoning with chemical compounds, including barbiturates).
Oral use; adults with swelling – 40 mg once a day (up to 80-120 mg / day), after increasing diuresis, the dose is reduced to a maintenance dose of 40 mg every other day.
From the side of metabolism: hypovolemia, hypokalemia, hyponatremia, hypochloremia, hypokalemic metabolic alkalosis (as a result of these disorders – arterial hypotension, dizziness, dry mouth, thirst, arrhythmia, muscle weakness, convulsions), hyperuricemia (with possible exacerbation of gout), hyperglycemia .
Allergic reactions: purpura, urticaria, exfoliative dermatitis, multiforme exudative erythema, vasculitis, necrotizing angiitis, itching, chills, fever, photosensitivity, anaphylactic shock.